LITTLE KNOWN FACTS ABOUT CONOLIDINE.

These benefits, along with a earlier report demonstrating that a little-molecule ACKR3 agonist CCX771 displays anxiolytic-like conduct in mice,two aid the strategy of targeting ACKR3 as a singular method to modulate the opioid technique, which could open new therapeutic avenues for opioid-associated Issues.These effects recommend that conolidine is